| + |
DGUOK | up-regulates quantity
chemical modification
|
2'-deoxyinosine 5'-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280576 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17073823 |
DGUOK [dG (deoxyguanosine) kinase] is one of the two mitochondrial deoxynucleoside salvage pathway enzymes involved in precursor synthesis for mtDNA (mitochondrial DNA) replication. DGUOK is responsible for the initial rate-limiting phosphorylation of the purine deoxynucleosides, using a nucleoside triphosphate as phosphate donor. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
2'-deoxyinosine | up-regulates quantity
precursor of
|
2'-deoxyinosine 5'-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280577 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17073823 |
DGUOK [dG (deoxyguanosine) kinase] is one of the two mitochondrial deoxynucleoside salvage pathway enzymes involved in precursor synthesis for mtDNA (mitochondrial DNA) replication. DGUOK is responsible for the initial rate-limiting phosphorylation of the purine deoxynucleosides, using a nucleoside triphosphate as phosphate donor. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MAPDA | up-regulates quantity
chemical modification
|
2'-deoxyinosine 5'-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280505 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29884623 |
We show that Arabidopsis thaliana and human cells require an N6-mAMP deaminase (ADAL, renamed MAPDA) to catabolize N6-mAMP to inosine monophosphate in vivo by hydrolytically removing the aminomethyl group. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
N(6)-methyl-dAMP(2-) | up-regulates quantity
precursor of
|
2'-deoxyinosine 5'-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280506 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29884623 |
We show that Arabidopsis thaliana and human cells require an N6-mAMP deaminase (ADAL, renamed MAPDA) to catabolize N6-mAMP to inosine monophosphate in vivo by hydrolytically removing the aminomethyl group. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |