3.0
Summary
| Name |  crizotinib
|
| Synonyms | (R)-crizotinib (ChEBI), crizotinib (WHO MedNet), crizotinib (WHO MedNet), crizotinib (KEGG DRUG), crizotinibum (WHO MedNet), PF 2341066 (ChemIDplus), PF-2341066 (ChemIDplus) |
| IUPAC | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine |
| Formula | C21H22Cl2FN5O |
| PRIMARY ID (Read more) |
CHEBI:64310 |
| Type | chemical |
| Relations | 4 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | crizotinib | down-regulates activity 
chemical inhibition
|
ALK | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | crizotinib | down-regulates
chemical inhibition
|
MET | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | crizotinib | down-regulates
chemical inhibition
|
ALK | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | crizotinib | down-regulates activity
chemical inhibition
|
MET | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |