| + |
NADP(3-) | up-regulates quantity 
precursor of
|
NADPH(4-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268078 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 33064660 |
Malic enzyme 1 (ME1) is a cytosolic protein that catalyzes the conversion of malate to pyruvate while concomitantly generating NADPH from NADP. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268111 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 34775382 |
6 PG undergoes oxidative decarboxylation by 6-phosphogluconate dehydrogenase (6PGD) producing Ru5P and the second NADPH molecule. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
PGD | down-regulates quantity 
chemical modification
|
NADP(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268112 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 34775382 |
6 PG undergoes oxidative decarboxylation by 6-phosphogluconate dehydrogenase (6PGD) producing Ru5P and the second NADPH molecule. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FASN | up-regulates quantity
chemical modification
|
NADP(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268087 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15507492 |
Human fatty acid synthase (FAS) is a complex homodimeric (552-kDa) enzyme that regulates the de novo biosynthesis of long-chain fatty acids. This cytosolic enzyme catalyzes the formation of 16 carbon (C16) palmitate, from acetyl-coenzyme A (acetyl-CoA) and malonyl-coenzyme A (malonyl-CoA) in the presence of NADPH.  |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
G6PD | down-regulates quantity
chemical modification
|
NADP(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268125 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24769394 |
G6PD catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconate and concomitantly reduces NADP+ to NADPH, which is the rate-limiting and primary control step of the NADPH-generating portion in the PPP. Thus, G6PD acts as a guardian of cellular redox potential during oxidative stress |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NADPH(4-) | up-regulates quantity
precursor of
|
NADP(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268088 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15507492 |
Human fatty acid synthase (FAS) is a complex homodimeric (552-kDa) enzyme that regulates the de novo biosynthesis of long-chain fatty acids. This cytosolic enzyme catalyzes the formation of 16 carbon (C16) palmitate, from acetyl-coenzyme A (acetyl-CoA) and malonyl-coenzyme A (malonyl-CoA) in the presence of NADPH.  |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ME1 | down-regulates quantity
chemical modification
|
NADP(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267722 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 33064660 |
Malic enzyme 1 (ME1) is a cytosolic protein that catalyzes the conversion of malate to pyruvate while concomitantly generating NADPH from NADP. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
NADP(3-)