| + |
BDH1 | down-regulates quantity 
chemical modification
|
NADH(2-) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-282494 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 40562122 |
β-Hydroxybutyrate dehydrogenase 1 (BDH1), a short-chain dehydrogenase located in the inner mitochondrial membrane, has been extensively studied for its critical role in ketone body metabolism. BDH1 catalyzes the interconversion between beta-hydroxybutyric acid (β-HB) and acetoacetic acid (AcAc) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
BDH1 | up-regulates quantity 
chemical modification
|
NADH(2-) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-282500 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 40562122 |
β-Hydroxybutyrate dehydrogenase 1 (BDH1), a short-chain dehydrogenase located in the inner mitochondrial membrane, has been extensively studied for its critical role in ketone body metabolism. BDH1 catalyzes the interconversion between beta-hydroxybutyric acid (β-HB) and acetoacetic acid (AcAc) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
BDH2 | up-regulates quantity
chemical modification
|
NADH(2-) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-282517 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16380372 |
Human DHRS6 is a previously uncharacterized member of the short chain dehydrogenases/reductase family and displays significant homologies to bacterial hydroxybutyrate dehydrogenases. Substrate screening reveals sole NAD+-dependent conversion of (R)-hydroxybutyrate to acetoacetate with Km values of about 10 mm, consistent with plasma levels of circulating ketone bodies in situations of starvation or ketoacidosis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
NADH(2-)