4.0
Summary
| Name |  CCL21
|
| Full Name | C-C motif chemokine 21 |
| Synonyms | 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21 | SCYA21 |
| Primary ID | O00585 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Pathways | GPCR_Breast Cancer |
| Function | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
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