+ |
SOSTDC1 | down-regulates activity
|
WNT9B |
0.28 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-242739 |
|
|
Mus musculus |
|
pmid |
sentence |
22829579 |
Our laboratory identified an almost twofold upregulation of sclerostin domain-containing 1 (Sostdc1; also referred to as WISE, USAG-1, ectodin), a dual Bmp/Wnt inhibitor, in postnatal day (P)1 pancreata from transgenic mice misexpressing hepatocyte nuclear factor (Hnf)6 in islet endocrine cells. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
WNT9B | up-regulates
binding
|
LRP5 |
0.592 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-132114 |
|
|
Homo sapiens |
|
pmid |
sentence |
15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
WNT9B | up-regulates
binding
|
CHRNA1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-195978 |
|
|
Homo sapiens |
Neuron |
pmid |
sentence |
22309736 |
We identified five wnts (wnt9a, wnt9b, wnt10b, wnt11, and wnt16) that are able to stimulate achr clustering, of which wnt9a and wnt11 are expressed abundantly in developing muscles. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Muscle |
+ |
WNT9B | up-regulates
binding
|
FZD3 |
0.607 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-132111 |
|
|
Homo sapiens |
|
pmid |
sentence |
15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
WNT9B | up-regulates
binding
|
LRP6 |
0.615 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-163552 |
|
|
Homo sapiens |
|
pmid |
sentence |
20093360 |
We find that wnt9b binds to a different part of the lrp6 extracellular domain |
|
Publications: |
1 |
Organism: |
Homo Sapiens |