Summary

Name SEPTIN4
Full Name Septin-4
Synonyms Apoptosis-related protein in the TGF-beta signaling pathway, ARTS, Bradeion beta, Brain protein H5, CE5B3 beta, Cell division control-related protein 2, hCDCREL-2, Cerebral protein 7, Peanut-like protein 2 | ARTS, C17orf47, PNUTL2, SEP4, SEPT4
Primary ID O43236
Links - -
Type protein
Relations 2
Function Filament-forming cytoskeletal GTPase (Probable). Plays an important role in male fertility and sperm motility (By similarity). During spermiogenesis, essential for the establishment of the annulus (a fibrous ring structure connecting the midpiece and the principal piece of the sperm flagellum) which is a requisite for the structural and mechanical integrity of the sperm (By similarity). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination SEPTIN4 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity img/direct_inhibition.png binding XIAP 0.2
Publications: 1 Organism: Chlorocebus Aethiops