3.0
Summary
| Name |  BCL2L11View Modifications |
| Full Name | Bcl-2-like protein 11 |
| Synonyms | Bcl2-L-11, Bcl2-interacting mediator of cell death | BIM |
| Primary ID | O43521-1 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | EGLN3 | up-regulates quantity by stabilization 
hydroxylation
|
BCL2L11 (isoform 1) | 0.258 |
| Publications: | 2 | Organism: | Homo Sapiens | |