3.0
Summary
| Name |  H2BC12View Modifications |
| Full Name | Histone H2B type 1-K |
| Synonyms | H2B K, HIRA-interacting protein 1 | H2BFT, HIRIP1 |
| Primary ID | O60814 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; FUNCTION |
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monoubiquitination
translation regulation