Summary

Name ASTN2
Full Name Astrotactin-2
Synonyms ASTN2_HUMAN | KIAA0634
Primary ID O75129
Links - -
Type protein
Relations 2
Function Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6).

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Relations

Regulator Mechanism target score
+ down-regulates quantity img/direct_inhibition.png binding ASTN1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Neuron_migration 0.7
Publications: 1 Organism: Homo Sapiens