Relation Results

Summary

Name ATG12
Full Name Ubiquitin-like protein ATG12
Synonyms Autophagy-related protein 12, APG12-like | APG12, APG12L
Primary ID O94817
Links - -
Type protein
Relations 4
Pathways Autophagy
Function Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 ...
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Type: Score: Layout: SPV 
0.70.8790.9370.868ATG12Autophagosome_formationATG10ATG7ATG12/5/16L1

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Relations
Regulator
Mechanism
target
score ℹ
+ ATG12up-regulates img/indirect-activation.png Autophagosome_formation 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-219396 Saccharomyces cerevisiae
pmid sentence
Dissecting the role of the Atg12-Atg5-Atg16 complex during autophagosome formation
Publications: 1 Organism: Saccharomyces Cerevisiae
Pathways:Autophagy
+ ATG10up-regulates img/direct-activation.png binding ATG12 0.879
Identifier Residue Sequence Organism Cell Line
SIGNOR-180129 Homo sapiens
pmid sentence
Analogous to ubiquitination, atg12 is conjugated to atg5 by atg7--an e1-like protein--and atg10--an e2-like protein.
Publications: 1 Organism: Homo Sapiens
Pathways:Autophagy
+ ATG7up-regulates img/direct-activation.png binding ATG12 0.937
Identifier Residue Sequence Organism Cell Line
SIGNOR-180132 Homo sapiens
pmid sentence
Analogous to ubiquitination, atg12 is conjugated to atg5 by atg7--an e1-like protein--and atg10--an e2-like protein.
Publications: 1 Organism: Homo Sapiens
Pathways:Autophagy
+ ATG12form complex img/form-complex.png binding ATG12/5/16L1 0.868
Identifier Residue Sequence Organism Cell Line
SIGNOR-226689 Homo sapiens
pmid sentence
Atg12 is conjugated to atg5 and forms an approximately 800-kda protein complex with atg16l (referred to as atg16l complex).
Publications: 1 Organism: Homo Sapiens
Tissue: HEK-293 Cell
Pathways:Autophagy
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