Summary

Name DUSP14
Full Name Dual specificity protein phosphatase 14
Synonyms EC 3.1.3.16, EC 3.1.3.48, MKP-1-like protein tyrosine phosphatase, MKP-L, Mitogen-activated protein kinase phosphatase 6, MAP kinase phosphatase 6, MKP-6 | MKP6
Primary ID O95147
Links - -
Type protein
Relations 2
Function Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases. Plays a negative role in TCR signaling by dephosphorylating MAP3K7 adapter TAB1 leading to its inactivation (PubMed:24403530). {ECO:0000269|PubMed:24403530}.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination DUSP14 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation TAB1 0.303
Publications: 1 Organism: Homo Sapiens