| + |
SMAD5 | up-regulates quantity 
transcriptional regulation
|
GADD45G |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268942 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 22219353 |
Chromatin immunoprecipitation (ChIP) revealed a subset of the BIG (BMP4 induced genes) signature, including Satb2, Smad6, Hand1, Gadd45γ and Gata3, that was bound by Smad1/5 in the developing mandible, revealing direct Smad-mediated regulation |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
SMAD1 | up-regulates quantity
transcriptional regulation
|
GADD45G |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268937 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 22219353 |
Chromatin immunoprecipitation (ChIP) revealed a subset of the BIG (BMP4 induced genes) signature, including Satb2, Smad6, Hand1, Gadd45γ and Gata3, that was bound by Smad1/5 in the developing mandible, revealing direct Smad-mediated regulation |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
GADD45G | down-regulates activity 
binding
|
CDK11A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273025 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 26885618 |
Western blot analysis for SPDEF revealed that overexpression of GADD45α, β and γ prevents SPDEF degradation mediated by CDK11p58 |We identified CDK11p58 as an interaction partner of GADD45α by co-immunoprecipitation analysis. We corroborated these data by co-immunoprecipitation in vitro translation assays, showing that all three members of the GADD45 family interact with CDK11p58. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
GADD45G
- 
- 