| + |
MPC2 | form complex 
binding
|
Mitochondrial pyruvate carrier complex, testis variant |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281076 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35278701 |
We determined that the functional unit of human MPC is a hetero-dimer. In this study, we established in vitro systems relying on recombinant, heterologously expressed human MPC proteins to investigate the key features of inhibitor binding. First, we showed that the human MPC is a hetero-dimeric complex mediating pyruvate transport in proteoliposomes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MPC2 | form complex
binding
|
Mitochondrial pyruvate carrier complex |
0.822 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280962 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 40691140 |
The Mitochondrial Pyruvate Carrier (MPC) bridges cytosolic and mitochondrial metabolism by transporting pyruvate into mitochondria for ATP production and biosynthesis of various essential molecules. MPC functions as a heterodimer composed of MPC1 and MPC2 in most mammalian cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
MPC2
- 
- 