Summary

Name FSHB
Full Name Follitropin subunit beta
Synonyms Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain |
Primary ID P01225
Links - -
Type protein
Relations 2
Function Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (PubMed:2494176, PubMed:24692546). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432).

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation FSHB 0.378
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation FSHB 0.354
Publications: 1 Organism: Mus Musculus