Summary

Name POU2F2
Full Name POU domain, class 2, transcription factor 2
Synonyms Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2 | OCT2, OTF2
Primary ID P09086
Links - -
Type protein
Relations 2
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654). Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding POU2F2 0.579
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding POU2F2 0.325
Publications: 1 Organism: Mus Musculus