3.0
Summary
| Name |  HNRNPA1View Modifications |
| Full Name | Heterogeneous nuclear ribonucleoprotein A1 |
| Synonyms | hnRNP A1, Helix-destabilizing protein, Single-strand RNA-binding protein, hnRNP core protein A1 | HNRPA1 |
| Primary ID | P09651 |
| Links |  -  -  |
| Type | protein |
| Relations | 12 |
| Function | Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (PubMed:17371836). May bind to specific miRNA hairpins (PubMed:28431233). Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1 (PubMed:31498791). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | AKT | down-regulates 
phosphorylation
|
HNRNPA1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AKT1 | down-regulates
phosphorylation
|
HNRNPA1 | 0.423 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKCA | down-regulates
phosphorylation
|
HNRNPA1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | D-glucitol | down-regulates activity 
relocalization
|
HNRNPA1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | TNPO1 | up-regulates activity 
relocalization
|
HNRNPA1 | 0.59 |
| Publications: | 1 | |||
| + | TARDBP | up-regulates
post transcriptional regulation
|
HNRNPA1 | 0.414 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HNRNPA1 | up-regulates quantity by expression
transcriptional regulation
|
TRA2B | 0.683 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | UBQLN2 | up-regulates quantity by stabilization
binding
|
HNRNPA1 | 0.471 |
| Publications: | 1 | |||
| + | MYC | up-regulates quantity by expression
transcriptional regulation
|
HNRNPA1 | 0.47 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HNRNPA1 | up-regulates 
|
Alternative_Splicing_Regulation | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Osmotic_stress | down-regulates activity
relocalization
|
HNRNPA1 | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |