Summary

Name TFPI
Full Name Tissue factor pathway inhibitor
Synonyms TFPI, Extrinsic pathway inhibitor, EPI, Lipoprotein-associated coagulation inhibitor, LACI | LACI, TFPI1
Primary ID P10646
Links - -
Type protein
Relations 1
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding VLDLR 0.26
Publications: 1 Organism: Homo Sapiens