| + |
NFATC1 | up-regulates quantity by expression 
transcriptional regulation
|
MYH7 |
0.278 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251956 |
|
|
Mus musculus |
C2C12 Cell |
| pmid |
sentence |
| 17111365 |
Transient transfection assays demonstrated that the calcineurin/NFATc1 signaling pathway is essential for MyHCbeta promoter activation during transformation of C2C12 myotubes but is not sufficient for complete fast MyHCIId/x promoter inhibition. Along with NFATc1, myocyte enhancer factor-2D (MEF-2D) and the myogenic transcription factor MyoD transactivated the MyHCbeta promoter in calcium-ionophore-treated myotubes in a calcineurin-dependent manner. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
EDN1 | up-regulates quantity by expression
transcriptional regulation
|
MYH7 |
0.284 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251955 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12847114 |
βMHC expression was markedly augmented by PE and ET, suggesting the transformation of myosin. endothelin-1 (ET) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MYOD1 | up-regulates quantity by expression
transcriptional regulation
|
MYH7 |
0.397 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251958 |
|
|
Mus musculus |
C2C12 Cell |
| pmid |
sentence |
| 17111365 |
Transient transfection assays demonstrated that the calcineurin/NFATc1 signaling pathway is essential for MyHCbeta promoter activation during transformation of C2C12 myotubes but is not sufficient for complete fast MyHCIId/x promoter inhibition. Along with NFATc1, myocyte enhancer factor-2D (MEF-2D) and the myogenic transcription factor MyoD transactivated the MyHCbeta promoter in calcium-ionophore-treated myotubes in a calcineurin-dependent manner. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
LIF | up-regulates quantity by expression
transcriptional regulation
|
MYH7 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251959 |
|
|
Rattus norvegicus |
|
| pmid |
sentence |
| 10212267 |
Increase of protein synthesis rate and β-MHC gene expression in cardiac myocytes by ET-1 and LIF. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
MEF2D | up-regulates quantity by expression
transcriptional regulation
|
MYH7 |
0.342 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251957 |
|
|
Mus musculus |
C2C12 Cell |
| pmid |
sentence |
| 17111365 |
Transient transfection assays demonstrated that the calcineurin/NFATc1 signaling pathway is essential for MyHCbeta promoter activation during transformation of C2C12 myotubes but is not sufficient for complete fast MyHCIId/x promoter inhibition. Along with NFATc1, myocyte enhancer factor-2D (MEF-2D) and the myogenic transcription factor MyoD transactivated the MyHCbeta promoter in calcium-ionophore-treated myotubes in a calcineurin-dependent manner. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
MYH7
- 
- 