3.0
Summary
| Name |  BPI
|
| Full Name | Bactericidal permeability-increasing protein |
| Synonyms | BPI, CAP 57 | |
| Primary ID | P17213 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |
transcriptional regulation