| + |
MYC | down-regulates quantity by repression 
transcriptional regulation
|
HLA-G |
0.263 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254607 |
|
|
Homo sapiens |
Melanoma Cell |
| pmid |
sentence |
| 8206526 |
In melanoma, HLA class I expression is suppressed by overexpression of the c-myc oncogene. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CIITA |
transcriptional regulation
|
HLA-G |
0.459 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254021 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 11137218 |
The X1 box is the binding site for the ubiquitous RFX complex consisting of three subunits; the X2 box is bound by the X2BP/ATF/CREB family factors. The basic S-X-Y regulatory module interacts with CIITA, which is expressed constitutively in APCs, but may be inducible in others cell types by IFN-gamma|We propose that the X region in the HLA-G gene promoter might participate to the combination of factors which play a role in HLA-G gene activation |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HLA-G | up-regulates 
binding
|
LILRB1 |
0.763 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-134180 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15718280 |
Hla-g binds a limited repertoire of peptides and interacts with the inhibitory leukocyte ig-like receptors lir-1 and lir-2 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HLA-G | up-regulates
binding
|
KLRC1 |
0.628 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-56714 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9560253 |
Current models of nk cell function have supposed that the cd94/nkg2a heterodimer is interacting with an epitope common to classical hla class i |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HLA-G | up-regulates
binding
|
KIR2DL4 |
0.756 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-66132 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10190900 |
Recombinant soluble kir2dl4 binds to cells expressing hla-g but not to cells expressing other hla class i molecules. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
HLA-G
- 
- 