Summary

Name CXCL2
Full Name C-X-C motif chemokine 2
Synonyms Growth-regulated protein beta, Gro-beta, Macrophage inflammatory protein 2-alpha, MIP2-alpha | GRO2, GROB, MIP2A, SCYB2
Primary ID P19875
Links - -
Type protein
Relations 3
Pathways iCAF signaling in PDAC, Chemokines PDAC
Function Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.

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Relations

Regulator Mechanism target score ℹ
+ CXCL2up-regulates img/indirect-activation.png Neutrophil_activation 0.7
Publications: 1 Organism: Homo Sapiens
+ CXCL2up-regulates activity img/direct-activation.png binding CXCR2 0.752
Publications: 1 Organism: Homo Sapiens
+ ZC3H12Adown-regulates quantity by destabilization img/direct_inhibition.png post transcriptional regulation CXCL2
Publications: 1 Organism: Homo Sapiens