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Summary
Name
NCF2
Full Name
Neutrophil cytosol factor 2
Synonyms
NCF-2, 67 kDa neutrophil oxidase factor, NADPH oxidase activator 2, Neutrophil NADPH oxidase factor 2, p67-phox | NOXA2, P67PHOX
Primary ID
P19878
Links
-
-
Type
protein
Relations
1
Function
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
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by mechanism
none
transcriptional regulation
by effect
none
up-regulates quantity by expression
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
U-937 cell
Relations
Regulator
Mechanism
target
score
ℹ
+
IRF8
up-regulates quantity by expression
transcriptional regulation
NCF2
0.3
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-222789
Homo sapiens
U-937 Cell
pmid
sentence
11483597
we found that tyrosine phosphorylated ICSBP activates CYBB and NCF2 transcription, during late myeloid differentiation, by interacting with PU.1, IRF1 and CBP.
Publications:
1
Organism:
Homo Sapiens