4.0
Summary
| Name |  IGFBP5
|
| Full Name | Insulin-like growth factor-binding protein 5 |
| Synonyms | IBP-5, IGF-binding protein 5, IGFBP-5 | IBP5 |
| Primary ID | P24593 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Pathways | Satellite: miRNA network |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MYOD1/SWI/SNF complex | up-regulates quantity by expression 
transcriptional regulation
|
IGFBP5 | 0.312 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Muscle | |||
| + | IGFBP5 | up-regulates activity
|
Skeletal_muscle_differentiation | 0.7 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | mir-143 | down-regulates quantity 
post transcriptional regulation
|
IGFBP5 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |