3.0
Summary
| Name |  CTSSView Modifications |
| Full Name | Cathepsin S |
| Synonyms | CATS_HUMAN | |
| Primary ID | P25774 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Pathways | MHC class II antigen presentation |
| Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CTSS | down-regulates quantity by destabilization 
cleavage
|
BGLAP | 0.309 |
| Publications: | 1 | Organism: | In Vitro | |
| + | TFE3 | up-regulates quantity by expression 
transcriptional regulation
|
CTSS | 0.271 |
| Publications: | 1 | |||
| + | CTSS | down-regulates quantity
chemical modification
|
oligopeptide | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CTSS | up-regulates
|
ECM_disassembly | 0.7 |
| Publications: | 1 | |||
| + | CTSS | up-regulates quantity 
chemical modification
|
peptide antigen | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |