Summary

Name HLA-DMB
Full Name HLA class II histocompatibility antigen, DM beta chain
Synonyms MHC class II antigen DMB, Really interesting new gene 7 protein | DMB, RING7
Primary ID P28068
Links - -
Type protein
Relations 4
Function Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HLA-DMB 0.377
Publications: 2 Organism: Homo Sapiens, In Vitro
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HLA-DMB 0.363
Publications: 2 Organism: Homo Sapiens