| + |
TM4SF1 | up-regulates activity 
relocalization
|
SDCBP2 |
0.413 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272401 |
|
|
|
|
| pmid |
sentence |
| 33015133 |
TM4SF1 functions as a membrane adaptor connecting DDR1 to syntenin2. |
|
| Publications: |
1 |
| + |
DDR1 | up-regulates activity
binding
|
TM4SF1 |
0.442 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272400 |
|
|
|
|
| pmid |
sentence |
| 30187813 |
Gao et al have demonstrated that in metastatic breast cancer cell, DDR1 interacts with cell surface Transmembrane 4 L Six Family Member 1 (TM4SF1) and regulates tumor dormancy and reactivation [3]. The interaction between DDR1 and TM4SF1 is collagen dependent and control Protein Kinase C Alpha (PKCa) mediated downstream JAK-STAT signaling pathway [3] (Figure 3). Interestingly the data also showed that TM4SF1 failed to interact with DDR2. |
|
| Publications: |
1 |
| + |
TM4SF1 | up-regulates activity
binding
|
DVL2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272402 |
|
|
|
|
| pmid |
sentence |
| 33015133 |
TM4SF1 is a partner of DVL2 and positively modulates Wnt/beta-catenin signaling by enhancing DVL2-Axin interaction. |
|
| Publications: |
1 |
3.0
TM4SF1
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- 