| + |
HOXA11 | down-regulates quantity by repression 
transcriptional regulation
|
HOXA10 |
0.3 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254469 |
|
|
Homo sapiens |
Megakaryocyte Cell Line |
| pmid |
sentence |
| 17688409 |
Chromatin immunoprecipitation (ChIP) and chloramphenicol acetyl transferase (CAT) assays confirm that HOXA11 binds to the putative binding site, resulting in repression of HOXA10 expression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HOXA11 | up-regulates quantity by expression 
transcriptional regulation
|
PRL |
0.363 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261630 |
|
|
Homo sapiens |
Endometrial Stromal Cell |
| pmid |
sentence |
| 19727442 |
HoxA-11 enhanced upregulation of PRL only in differentiated cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KDM6A | up-regulates quantity by expression
transcriptional regulation
|
HOXA11 |
0.267 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260021 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24561908 |
Evidence for direct involvement of UTX in regulation of HOX gene activity was demonstrated through UTX knockdown experiments in HEK293T cells in which loss of UTX induced transcriptional repression of HOXA and HOXC clusters. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
HOXA11
- 
- 