Summary

Name H2BC3
Full Name Histone H2B type 1-B
Synonyms Histone H2B.1, Histone H2B.f, H2B/f | H2BFF
Primary ID P33778
Links - -
Type protein
Relations 5
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png monoubiquitination H2BC3 0.2
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation H2BC3 0.2
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation H2BC3 0.2
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation H2BC3 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png translation regulation H2BC3 0.2
Publications: 1 Organism: Homo Sapiens