3.0
Summary
| Name |  MYH10View Modifications |
| Full Name | Myosin-10 |
| Synonyms | Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, non-muscle IIb, Non-muscle myosin heavy chain B, NMMHC-B, Non-muscle myosin heavy chain IIb, NMMHC II-b, NMMHC-IIB |
| Primary ID | P35580 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCZ | down-regulates 
phosphorylation
|
MYH10 | 0.272 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MEF2C | up-regulates quantity by expression 
transcriptional regulation
|
MYH10 | 0.352 |
| Publications: | 1 | Organism: | Mus Musculus | |
| Tissue: | Skeletal Muscle | |||
| + | POU2F1 | up-regulates quantity by expression
transcriptional regulation
|
MYH10 | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | MEF2D | up-regulates quantity by expression
transcriptional regulation
|
MYH10 | 0.328 |
| Publications: | 1 | Organism: | Mus Musculus | |
| Tissue: | Skeletal Muscle | |||
| + | MEF2A | up-regulates quantity by expression
transcriptional regulation
|
MYH10 | 0.323 |
| Publications: | 1 | Organism: | Mus Musculus | |
| Tissue: | Skeletal Muscle | |||