Name
|
SOAT1
|
Full Name |
Sterol O-acyltransferase 1 |
Synonyms |
Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1 | ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT |
Primary ID |
P35610 |
Links |
- - |
Type |
protein |
Relations |
3 |
Inhibitors |
Avasimibe
|
Function |
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol (PubMed:16154994, PubMed:16647063, PubMed:9020103, PubMed:32433614, PubMed:32433613). Plays a role in lipoprotein assembly and dietary cholesterol absorption (PubMed:16154994, PubMed:9020103). Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate |