+ |
CTSK | up-regulates
|
ECM_disassembly |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253318 |
|
|
|
|
pmid |
sentence |
11920402 |
Cathepsins K and S have been implicated in various aspects of extracellular matrix degradation and inflammatory responses. |
|
Publications: |
1 |
+ |
TNF | up-regulates quantity by expression
transcriptional regulation
|
CTSK |
0.367 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253317 |
|
|
|
|
pmid |
sentence |
11920402 |
This is supported by our finding that inflammatory cytokines such as IL-1b and TNFa increase the expres- sion of cathepsin K mRNA 6–8-fold and increase the secretion of the mature enzyme. |
|
Publications: |
1 |
+ |
Odanacatib | down-regulates
chemical inhibition
|
CTSK |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-195007 |
|
|
Homo sapiens |
|
pmid |
sentence |
Other |
|
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
IL1B | up-regulates quantity by expression
transcriptional regulation
|
CTSK |
0.34 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253316 |
|
|
|
|
pmid |
sentence |
11920402 |
This is supported by our finding that inflammatory cytokines such as IL-1b and TNFa increase the expres- sion of cathepsin K mRNA 6–8-fold and increase the secretion of the mature enzyme. |
|
Publications: |
1 |