Summary

Name SLC11A2
Full Name Natural resistance-associated macrophage protein 2
Synonyms NRAMP 2, Divalent cation transporter 1, Divalent metal transporter 1, DMT-1, Solute carrier family 11 member 2 | DCT1, DMT1, NRAMP2
Primary ID P49281
Links - -
Type protein
Relations 1
Function Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.

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Relations

Regulator Mechanism target score
+ down-regulates quantity img/direct_inhibition.png ubiquitination SLC11A2 0.306
Publications: 1 Organism: Cricetulus Griseus