4.0
Summary
| Name |  TUFMView Modifications |
| Full Name | Elongation factor Tu, mitochondrial |
| Synonyms | EF-Tu, P43 | |
| Primary ID | P49411 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy. |
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phosphorylation