4.0
Summary
| Name |  LIG3View Modifications |
| Full Name | DNA ligase 3 |
| Synonyms | DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3 |
| Primary ID | P49916 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
phosphorylation
binding