Summary

Name ARHGDIB
Full Name Rho GDP-dissociation inhibitor 2
Synonyms Rho GDI 2, Ly-GDI, Rho-GDI beta | GDIA2, GDID4, RAP1GN1
Primary ID P52566
Links - -
Type protein
Relations 4
Function Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation ARHGDIB 0.2
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation ARHGDIB 0.41
Publications: 2 Organism: Homo Sapiens
+ up-regulates quantity by stabilization img/direct-activation.png polyubiquitination ARHGDIB 0.2
Publications: 1 Organism: Homo Sapiens