3.0
Summary
| Name |  CAPZA1View Modifications |
| Full Name | F-actin-capping protein subunit alpha-1 |
| Synonyms | CapZ alpha-1 |
| Primary ID | P52907 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Inhibitors | 1D-myo-inositol 1,4,5-trisphosphate; phosphatidylinositol bisphosphate |
| Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CSNK2A1 | up-regulates 
phosphorylation
|
CAPZA1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CAPZA1 | up-regulates quantity
binding
|
F-actin_assembly | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RCSD1 | up-regulates
binding
|
CAPZA1 | 0.689 |
| Publications: | 1 | Organism: | In Vitro | |
| + | 1D-myo-inositol 1,4,5-trisphosphate | down-regulates activity 
chemical inhibition
|
CAPZA1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | phosphatidylinositol bisphosphate | down-regulates activity
chemical inhibition
|
CAPZA1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |