Summary

Name SUB1
Full Name Activated RNA polymerase II transcriptional coactivator p15
Synonyms Positive cofactor 4, PC4, SUB1 homolog, p14 | PC4, RPO2TC1
Primary ID P53999
Links - -
Type protein
Relations 1
Function General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding REST-CoREST 0.324
Publications: 1 Organism: Homo Sapiens