Summary

Name RAD23A
Full Name UV excision repair protein RAD23 homolog A
Synonyms HR23A, hHR23A |
Primary ID P54725
Links - -
Type protein
Relations 4
Function Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; FUNCTION

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Relations

Regulator Mechanism target score
+ up-regulates img/indirect-activation.png RAD23A 0.7
Publications: 1
+ up-regulates img/indirect-activation.png RAD23A 0.587
Publications: 1
+ img/unknown.png ubiquitination RAD23A 0.297
Publications: 1 Organism: In Vitro
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination RAD23A 0.502
Publications: 1 Organism: Chlorocebus Aethiops