+ |
WNT4 | up-regulates
binding
|
LRP5 |
0.636 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-131832 |
|
|
Homo sapiens |
|
pmid |
sentence |
15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
WNT4 | up-regulates
|
MYF5 |
0.299 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-60370 |
|
|
Homo sapiens |
|
pmid |
sentence |
9753670 |
Wnt4, wnt5a and wnt6 exert an intermediate effect activating both myf5 and myod equivalently in paraxial mesoderm. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Muscle, Skeletal Muscle |
+ |
SFRP1 | down-regulates
binding
|
WNT4 |
0.721 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-106556 |
|
|
Homo sapiens |
|
pmid |
sentence |
11287180 |
Sfrp-1 binds wnt-4 with considerable avidity and inhibits the dna-binding activity of tcf, an effector of wnt signaling, |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Kidney |
+ |
SOSTDC1 | down-regulates activity
|
WNT4 |
0.283 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-242707 |
|
|
Mus musculus |
|
pmid |
sentence |
22829579 |
Our laboratory identified an almost twofold upregulation of sclerostin domain-containing 1 (Sostdc1; also referred to as WISE, USAG-1, ectodin), a dual Bmp/Wnt inhibitor, in postnatal day (P)1 pancreata from transgenic mice misexpressing hepatocyte nuclear factor (Hnf)6 in islet endocrine cells. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
WNT4 | up-regulates
binding
|
LRP6 |
0.635 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-131835 |
|
|
Homo sapiens |
|
pmid |
sentence |
15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
WNT4 | up-regulates
|
MYOD1 |
0.318 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-60373 |
|
|
Homo sapiens |
|
pmid |
sentence |
9753670 |
Wnt4, wnt5a and wnt6 exert an intermediate effect activating both myf5 and myod equivalently in paraxial mesoderm. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Muscle, Skeletal Muscle |