+ |
GTF2I | up-regulates quantity by expression
transcriptional regulation
|
GSC |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268536 |
|
|
|
|
pmid |
sentence |
16611241 |
For example, TFII-I binds to the Inr element of the T cell receptor Vbeta gene and activates its transcription in reporter gene assays (Cheriyath et al. 1998). TFII-I also activates transcription of c-fos and Goosecoid through binding to the serum response element and the distal element, respectively (Grueneberg et al. 1997; Ku et al. 2005). |
|
Publications: |
1 |
+ |
GSC | down-regulates quantity by repression
transcriptional regulation
|
EPHA7 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261613 |
|
|
Mus musculus |
P-19 Cell |
pmid |
sentence |
9417125 |
We demonstrate that Goosecoid can act as a repressor of its own promoter activity in transient co-transfection experiments in mouse P19 cells and in Xenopus embryos. Autorepression depends on the presence of the homeodomain and is mediated through the prd element more proximal to the transcriptional start site. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
EVX1 | down-regulates quantity by repression
transcriptional regulation
|
GSC |
0.256 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254139 |
|
|
Homo sapiens |
Embryonic Stem Cell |
pmid |
sentence |
22178155 |
We found that EVX1 repressed GSC expression and promoted formation of posterior streak-like progeny in response to BMP4, and conversely that GSC repressed EVX1 expression and was required for development of anterior streak-like progeny in response to activin. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
GSC | down-regulates quantity by repression
transcriptional regulation
|
EVX1 |
0.256 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254140 |
|
|
Homo sapiens |
Embryonic Stem Cell |
pmid |
sentence |
22178155 |
We found that EVX1 repressed GSC expression and promoted formation of posterior streak-like progeny in response to BMP4, and conversely that GSC repressed EVX1 expression and was required for development of anterior streak-like progeny in response to activin. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |