Summary

Name NRG3
Full Name Pro-neuregulin-3, membrane-bound isoform
Synonyms Pro-NRG3
Primary ID P56975
Links - -
Type protein
Relations 3
Function Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding ERBB4 0.738
Publications: 3 Organism: Homo Sapiens
Tissue: Muscle