Summary

Name YWHAE
Full Name 14-3-3 protein epsilon
Synonyms 14-3-3E
Primary ID P62258
Links - -
Type protein
Relations 3
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm (PubMed:12917326).

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding CDKN1B 0.20
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding NEFL 0.43
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding NDEL1 0.71
Publications: 1 Organism: Homo Sapiens