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Summary
Name
SKOR1
Full Name
SKI family transcriptional corepressor 1
Synonyms
Functional Smad-suppressing element on chromosome 15, Fussel-15, LBX1 corepressor 1, Ladybird homeobox corepressor 1 | CORL1, FUSSEL15, LBXCOR1
Primary ID
P84550
Links
-
-
Type
protein
Relations
1
Function
Acts as a transcriptional corepressor of LBX1 (By similarity). Inhibits BMP signaling.
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by mechanism
none
binding
by effect
none
down-regulates activity
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
HEK-293 cell
Relations
Regulator
Mechanism
target
score
ℹ
+
SKOR1
down-regulates activity
binding
LBX1
0.576
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-238004
Homo sapiens
HEK-293 Cell
pmid
sentence
15528197
Furthermore, Corl1 interacted with Lbx1 and cooperatively repressed transcription, suggesting that it acts as a transcriptional corepressor for Lbx1 in regulating cell fate determination in the dorsal spinal cord.
Publications:
1
Organism:
Homo Sapiens