Relation Results

Summary

Name CPSF1
Full Name Cleavage and polyadenylation specificity factor subunit 1
Synonyms Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit | CPSF160
Primary ID Q10570
Links - -
Type protein
Relations 1
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AA ...
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Type: Score: Layout: SPV 
0.941CPSF1CPSF complex

Relations

Regulator
Mechanism
target
score
+ form complex img/form-complex.png binding CPSF complex 0.941
Identifier Residue Sequence Organism Cell Line
SIGNOR-121646 Homo sapiens
pmid sentence
Recombinant hfip1 is sufficient to stimulate the in vitro polyadenylation activity of pap in a u-rich element-dependent manner. hfip1, cpsf160 and pap form a ternary complex in vitro, suggesting that hfip1 and cpsf160 act together in poly(a) site recognition and in cooperative recruitment of pap to the rna.
Publications: 1 Organism: Homo Sapiens
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