Summary

Name BPTF
Full Name Nucleosome-remodeling factor subunit BPTF
Synonyms Bromodomain and PHD finger-containing transcription factor, Fetal Alz-50 clone 1 protein, Fetal Alzheimer antigen | FAC1, FALZ
Primary ID Q12830
Links - -
Type protein
Relations 1
Function Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.

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Relations

Regulator Mechanism target score ℹ
+ BPTFform complex img/form-complex.png binding HNuRF 0.689
Publications: 1 Organism: Homo Sapiens