4.0
Summary
| Name |  MTAP
|
| Full Name | S-methyl-5'-thioadenosine phosphorylase |
| Synonyms | 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase | MSAP |
| Primary ID | Q13126 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
chemical modification