Summary

Name EFR3A
Full Name Protein EFR3 homolog A
Synonyms Protein EFR3-like | KIAA0143
Primary ID Q14156
Links - -
Type protein
Relations 2
Function Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3A probably acts as the membrane-anchoring component (PubMed:23229899). Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825).

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png binding PI4KA 0.488
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png binding KRAS 0.2
Publications: 1 Organism: Homo Sapiens