4.0
Summary
| Name |  SPIDR
|
| Full Name | DNA repair-scaffolding protein |
| Synonyms | Scaffolding protein involved in DNA repair | KIAA0146 |
| Primary ID | Q14159 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity. |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | SPIDR | form complex 
binding
|
SHU complex | |
| Publications: | 1 | Organism: | Homo Sapiens | |