4.0
Summary
| Name |  UBE3C
|
| Full Name | Ubiquitin-protein ligase E3C |
| Synonyms | HECT-type ubiquitin transferase E3C, HectH2 | KIAA0010, KIAA10 |
| Primary ID | Q15386 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. |
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ubiquitination
ubiquitination